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STAT+: Novo Nordisk stops two cardiovascular trials of drug aimed at lowering inflammation
RSS 官方收录 · 可信分层展示
关键摘要
诺和诺德终止ziltivekimab两项心血管炎症试验
- ziltivekimab在ZEUS试验已失败，未降低心梗死亡风险
- HERMES与ATHENA试验因无效被数据监委会叫停
- 诺和诺德周五通知研究者停止两项三期临床试验
AI 摘要 · 来源可核验
正文提要
Novo Nordisk has stopped two trials of a drug that aims to tame inflammation as a way to improve cardiovascular health, another blow for the approach.
The company said it had halted the HERMES and ATHENA trials of its drug, ziltivekimab, after a data monitoring committee found they were unlikely to succeed. Novo informed trial investigators on Friday.
The move follows the earlier failure of the drug in the ZEUS trial, which showed that the medicine, despite lowering markers of inflammation, did not reduce the risk of major clinical complications, including deaths and heart attacks.