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A knowledge-driven framework for predicting single-cell responses for unprofiled drugs
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关键摘要
Nature Machine Intelligence, Published online: 26 August 2026; doi:10.1038/s42256-026-01286-wFeng et al.…
- introduce MAP, an artificial intelligence framework that integrates bi…
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正文提要
Nature Machine Intelligence, Published online: 26 August 2026; doi:10.1038/s42256-026-01286-w
Feng et al. introduce MAP, an artificial intelligence framework that integrates biological mechanism knowledge to predict how cells respond to chemical perturbation, improving generalization to untested drugs and prioritizing cancer drug candidates in virtual screening.